Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to terrestrial arthropods: short-term
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
Recombinant spider silk protein is composed exclusively of naturally occurring oligopeptides.
Degradation products of spider silk proteins like peptides and amino acids are irreplaceable nutritional components for terrestrial organism. Terrestrial toxicity testing of recombinant eADF4(C48-CS25C) protein from E. Coli (K12 HMS174(DE3)-plasmid pAMS029) fermentation and subsequent purification is therefore considered as not scientifically necessary (see attached justification).


Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion