Registration Dossier
Registration Dossier
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EC number: 411-760-1 | CAS number: 116633-53-5 COMMERCIAL DRAGON II
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: no data on GLP
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.3 (Algal Inhibition test)
- Deviations:
- not specified
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- not specified
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Bis(N,N',N''-trimethyl-1,4,7-triazacyclononane)-trioxo-dimanganese (IV) di(hexafluorophosphate)monohydrate
- EC Number:
- 411-760-1
- EC Name:
- Bis(N,N',N''-trimethyl-1,4,7-triazacyclononane)-trioxo-dimanganese (IV) di(hexafluorophosphate)monohydrate
- Cas Number:
- 116633-53-5
- Molecular formula:
- C18 H42 Mn2 N6 O3 . 2 F6 P
- IUPAC Name:
- dimanganese(4+) bis(1,4,7-trimethyl-1,4,7-triazonane) bis(hexafluoro-λ⁵-phosphanuide) hydrate trioxidandiide
- Details on test material:
- no data
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
no data
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- no data
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- no data
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- no data
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Post exposure observation period:
- no data
Test conditions
- Hardness:
- no data
- Test temperature:
- no data
- pH:
- no data
- Dissolved oxygen:
- no data
- Salinity:
- no data
- Nominal and measured concentrations:
- no data
- Details on test conditions:
- A range of concentrations of the test substances (nominally 1.0-10.0 mg/l) was prepared in ISO medium. Nominal concentrations used. However, concentrations of test substance were not consistent over time being considerably below nominal at 0 hours.
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 3.2 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Remarks on result:
- other: no data
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 1.8 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Remarks on result:
- other: no data
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 8.7 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: no data
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 3.2 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: no data
- Details on results:
- no data
- Results with reference substance (positive control):
- no data
- Reported statistics and error estimates:
- no data
Any other information on results incl. tables
Algal growth inhibition: 96 -h ErC50 = 8.7 mg/l
NOEC = 3.2 mg/l.
Using an assessment factor of 1000 on the lowest E/LC50(algal growth inhibition) gives: PNEC for the aquatic compartment is 0.0086 mg/l. Inhibition of microbial activity: (17hr) EC5026.06 mg/l, NOEC = 5.20 mg/l. Sediment tests No sediment studies are available. The PNEC is therefore derived by equilibrium partitioning method from the aquatic
PNEC: PNEC for the sediment compartment = 0.00732 mg/kg
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Biomass: EbC50: 3.2 mg/l; NOEC: 1.8 mg/l
Growth rate: ErC50: 8.7 mg/l; NOEC: 3.2 mg/l - Executive summary:
iomass:
EbC50: 3.2 mg/l
NOEC: 1.8 mg/l
Growth rate
ErC50: 8.7 mg/l
NOEC: 3.2 mg/l
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