Registration Dossier
Registration Dossier
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EC number: 620-056-5 | CAS number: 874195-61-6
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish.
Key value for chemical safety assessment
Additional information
According to Regulation (EC) No. 1907/2006, Annex IX, Column 2, 9.1.6, long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicates the need to investigate further the effects on aquatic organisms.
According to the Guidance on information requirements and chemical safety assessment Chapter R.7b: Endpoint specific guidance, R.7.8.5.3 (ECHA, 2017), long-term testing with fish should only be conducted if it represents the most sensitive taxonomic group. The results indicate no higher sensitivity of fish compared to algae. In the available studies on the toxicity of triafamone (CAS 874195-61-6), algae were the most sensitive organism group resulting in the highest possible chronic classification Aquatic Chronic 1.
In addition, due to a low Kow of 1.5 (pH 4 and pH 7), the substance is not expected to bioaccumulate in aquatic organisms.
Furthermore, triafamone (CAS 874195-61-6) is used as herbicide. Thus, this substance has a specific impact on algae (plants) and not on aquatic fish and invertebrates. Therefore, algae (plants) are the most sensitive organism group.
Overall, since fish is not the most sensitive organism, the substance is not expected to bioaccumulate in aquatic organisms and as the substance has no specific impact on fish, no further long-term test with fish is proposed for triafamone (CAS 874195-61-6).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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