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EC number: 220-479-1
CAS number: 2781-00-2
Short description of key information on bioaccumulation potential result: No substance specific data on metabolism and kinetics are available. Based on physical-chemical characteristics, no or only limited absorption by the dermal and inhalation routes is expected, whereas oral absorption is more likely.
No substance specific data on metabolism and kinetics are
available, neither in human nor in animal.
Based on physical-chemical characteristics, particularly low water
solubility (<0.62 mg/l), octanol-water partition coefficient
(experimental log Kow is > 5.5, calculated log Kow :7.3) and low vapour
pressure ( 9
x 10-7 mbars at 20°C), no or only limited absorption
by the dermal and inhalation routes is expected, which is further
supported by the acute dermal toxicity study results. Moreover the
substance is not a skin irritant; therefore no increase of skin
absorption is expected.
Based on this log Pow
a logBCF was calculated: 3.96 (EPIWIN)
Based on the high log Kow and the very low water solubility, the
substance can be regarded as a lipophilic substance. Such a lipophilic
compound may be taken up by micellular solubilisation by oral route
exposure. Inhalation is not likely since the substance is a powder, and
with regards to granulometry.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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