Registration Dossier
Registration Dossier
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EC number: 442-070-9 | CAS number: 329039-38-5
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
59% biodegradation in 28 days (Manometric Respirometry Test)
Key value for chemical safety assessment
Additional information
One study investigating the degree of biodegradability of methyldiacetoxyisopropoxy silane (CAS No. 329039-38-5) in water is available. This test was conducted according to OECD 301F (Ready Biodegradability: Manometric Respirometry Test) under GLP conditions (Eickhoff, 2002). The test substance was incubated in activated sludge for 28 days at 23 ± 1 °C and biodegradation monitored by measuring the O2 consumption in the test vessels. Due to the rapid hydrolysis of the substance in water (within minutes-hours), analytical determination of the transformation products was performed (isopropanol, acetic acid and silanols). After 28 days, the biodegradation of the test substance reached 59%, and therefore it can be considered only moderately (but not readily) biodegradable. However, isopropanol (CAS No. 67-63-0) and acetic acid (CAS No. 64-19-7)(two of the main hydrolysis products) are well known to be readily biodegradable (OECD SIDS, 1997; HSDB, 2011).Therefore, methylsilanetriol (CAS No. 2445-53-6) is expected to be the metabolite showing low to moderate potential for biodegradation.
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