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EC number: 212-855-9
CAS number: 873-94-9
no further remarks
In an acute oral toxicity study according OECD 401 a single dose
of 2000 mg/kg 3,3,5-trimethylcyclohexanone was applied to 5 Wistar
rats/sex. The observation period was 14 days.
One male rat died 5 hours after application.
Within the first hours after treatment the animals showed
sedation, abdominal position, gasping breathing, and hypothermia, 24
hours after treatment they were free from symptoms.
No indications of treatment related macroscopic
organ changes were observed in the surviving animals, except for a focal thickening of the cutaneous gastric
mucosa in one female.
Under conditions of this study the LD50 value (oral) is above 2000
mg/kg bw in Wistar rats.
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