Registration Dossier
Registration Dossier
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EC number: 212-855-9 | CAS number: 873-94-9
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity was assessed in a limit test according to OECD 401 (Hüls, 1995). The LD 50 was above 2000 mg/kg bw.
Acute toxicity by inhalation was assessed in an acute inhalation toxicity study similar to OECD 403 (Hazleton, 1965). An LC 50 of 14.2 mg/l was concluded.
The dermal route was assessed in a limit test according to OECD 402 (Hüls, 1996). The LD50 was above 2000 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 14 200 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
Acute toxicity tests conducted in Wistar rats are available for all three routes. All studies are conducted similar or according to OECD guidelines. Both LD50 values for the oral and the dermal route were above a limit dose of 2000 mg/kg bw. An LC50 value for toxicity by inhalation could be derived (14.2 mg/l ).
Justification for classification or non-classification
An LC 50 of 14.2 mg/l has been concluded for 3,3,5-trimethylcyclohexanone. According to Regulation (EC) No 1272/2008 it has not been classified.
LD 50 values for oral and dermal exposure are above the limit dose of 2000 mg/kg bw. A classification is not warranted for these routes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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