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EC number: 201-063-9
CAS number: 77-85-0
Groups of 4 albino rabbits were evaluated for acute dermal toxicity
followling single dermal application
of 1000, 2150, 4640, 10000 mg/kg bw as paste for 24 hours and a post
exposure observation period of
7 days. A very mild degree of dermal irritation which disappeared at the
next day was the only clinical finding;
no animal died. Gross autopsy showed histopathological changes only in
the kidneys from 2150 mg/kg bw
onwards. In the absence of any deaths, the LD50 value after single
dermal administration is >10000 mg/kg bw (Celanese Corporation 1956).
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