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EC number: 201-063-9
CAS number: 77-85-0
Within a couple of hours after the dose, the animals that received 2.15 g/kg or more showed signs of fatigue, slow
respiration and ataxia. All the animals in the highest dose group died. Autopsies revealed kidney changes in the three
highest dose groups.
5 male rats were given single oral doses of 1000, 2150, 4640 10000 or
21500 mg/kg bw and observed for 7 days. 1000 mg/kg bw was tolerated
wihout any harm. Rats of the other groups appeared depressed, exhibited
lacrimation, slow and laboured respiration, ataxia, and other effects of
the limbs. 21500 mg/kg bw caused the death of all animals within 24
hours. Thus the LD50 value was determined 14700 mg/kg bw (Celanese
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