Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-063-9 | CAS number: 77-85-0
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental phase: 05 July 2016 to 17 August 2016. Report issued: 06 December 2016.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
Test material
- Reference substance name:
- Ethylidynetrimethanol
- EC Number:
- 201-063-9
- EC Name:
- Ethylidynetrimethanol
- Cas Number:
- 77-85-0
- Molecular formula:
- C5H12O3
- IUPAC Name:
- 2-(hydroxymethyl)-2-methylpropane-1,3-diol
- Test material form:
- solid: granular
Constituent 1
Results and discussion
Vapour pressure
- Key result
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0.003 Pa
Transition / decomposition
- Key result
- Transition / decomposition:
- no
Any other information on results incl. tables
A total of 6 runs were completed for the main sequence. Equilibrium with regard to vapour pressure was assessed to have been reached over the final 5 runs. Thus the final 5 runs have been used to calculate the definitive vapour pressure value for the test item. The results may represent rounded-off values obtained by calculations based on the exact raw data.
Recorded temperatures, mass differences and the resulting calculated values of vapour pressure are shown in the following tables:
Run 2
Table 1 – Run 2 Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1 ) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapour Pressure (Pa) |
Log10Vp |
35 |
308.15 |
0.003245173 |
12.03 |
1.203E-08 |
0.016700722 |
-1.777264751 |
36 |
309.15 |
0.003234676 |
13.94 |
1.394E-08 |
0.019352291 |
-1.713267605 |
37 |
310.15 |
0.003224246 |
13.88 |
1.388E-08 |
0.019268996 |
-1.715140913 |
38 |
311.15 |
0.003213884 |
16.18 |
1.618E-08 |
0.022461985 |
-1.648551861 |
39 |
312.15 |
0.003203588 |
18.31 |
1.831E-08 |
0.025418971 |
-1.594842034 |
40 |
313.15 |
0.003193358 |
23.81 |
2.381E-08 |
0.033054380 |
-1.480770983 |
41 |
314.15 |
0.003183193 |
26.43 |
2.643E-08 |
0.036691611 |
-1.435433216 |
42 |
315.15 |
0.003173092 |
31.63 |
3.163E-08 |
0.043910544 |
-1.357431187 |
43 |
316.15 |
0.003163056 |
36.12 |
3.612E-08 |
0.050143814 |
-1.299782637 |
44 |
317.15 |
0.003153082 |
39.54 |
3.954E-08 |
0.054891650 |
-1.260493714 |
45 |
318.15 |
0.003143171 |
49.34 |
4.934E-08 |
0.068496561 |
-1.164331234 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistical data using an unweighted least squares treatment.
Slope: -6.11 x 103
Standard error in slope: 255
Intercept: 18.0
Standard error in intercept: 0.814
The results obtained indicate the following vapour pressure relationship: Log10 (Vp (Pa)) = -6.11 x 103/ temp (K) + 18.0
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.48.
Run 3
Table 2 – Run 3 Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference (µg) |
Mass Difference (kg) |
Vapour Pressure (Pa) |
Log10Vp |
35 |
308.15 |
0.003245173 |
11.63 |
1.163E-08 |
0.016145420 |
-1.791950664 |
36 |
309.15 |
0.003234676 |
12.48 |
1.248E-08 |
0.017325437 |
-1.761315793 |
37 |
310.15 |
0.003224246 |
13.99 |
1.399E-08 |
0.019421704 |
-1.711712664 |
38 |
311.15 |
0.003213884 |
16.34 |
1.634E-08 |
0.022684106 |
-1.644278327 |
39 |
312.15 |
0.003203588 |
18.27 |
1.827E-08 |
0.025363441 |
-1.595791831 |
40 |
313.15 |
0.003193358 |
22.51 |
2.251E-08 |
0.031249647 |
-1.505154884 |
41 |
314.15 |
0.003183193 |
24.40 |
2.440E-08 |
0.033873451 |
-1.470140552 |
42 |
315.15 |
0.003173092 |
30.62 |
3.062E-08 |
0.042508405 |
-1.371525192 |
43 |
316.15 |
0.003163056 |
33.51 |
3.351E-08 |
0.046520465 |
-1.332355951 |
44 |
317.15 |
0.003153082 |
38.02 |
3.802E-08 |
0.052781501 |
-1.277518266 |
45 |
318.15 |
0.003143171 |
47.88 |
4.788E-08 |
0.066469707 |
-1.177376237 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 gives the following statistical data using an unweighted least squares treatment.
Slope: -6.07 x 103
Standard error in slope: 187
Intercept: 17.9
Standard error in intercept: 0.599
The results obtained indicate the following vapour pressure relationship: Log10 (Vp (Pa)) = -6.07 x 103/temp (K) + 17.9
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.49.
Run 4
Table 3 – Run 4 Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference(µg) |
Mass Difference(kg) |
Vapour Pressure(Pa) |
Log10Vp |
35 |
308.15 |
0.003245173 |
11.99 |
1.199E-08 |
0.016645192 |
-1.778711196 |
36 |
309.15 |
0.003234676 |
12.20 |
1.220E-08 |
0.016936726 |
-1.771170548 |
37 |
310.15 |
0.003224246 |
12.06 |
1.206E-08 |
0.016742370 |
-1.776183071 |
38 |
311.15 |
0.003213884 |
14.74 |
1.474E-08 |
0.020462896 |
-1.689032895 |
39 |
312.15 |
0.003203588 |
16.88 |
1.688E-08 |
0.023433765 |
-1.630157936 |
40 |
313.15 |
0.003193358 |
22.65 |
2.265E-08 |
0.031444003 |
-1.502462172 |
41 |
314.15 |
0.003183193 |
24.59 |
2.459E-08 |
0.034137220 |
-1.466771850 |
42 |
315.15 |
0.003173092 |
29.76 |
2.976E-08 |
0.041314504 |
-1.383897452 |
43 |
316.15 |
0.003163056 |
32.23 |
3.223E-08 |
0.044743497 |
-1.349270073 |
44 |
317.15 |
0.003153082 |
40.02 |
4.002E-08 |
0.055558013 |
-1.255253294 |
45 |
318.15 |
0.003143171 |
44.93 |
4.493E-08 |
0.062374351 |
-1.204993960 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.
Slope: -6.22 x 103
Standard error in slope: 351
Intercept: 18.3
Standard error in intercept: 1.12
The results obtained indicate the following vapor pressure relationship: Log10 (Vp (Pa)) = -6.22 x 103/temp (K) + 18.3
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.53.
Run 5
Table 4 – Run 5 Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference(µg) |
Mass Difference(kg) |
Vapour Pressure(Pa) |
Log10Vp |
35 |
308.15 |
0.003245173 |
11.57 |
1.157E-08 |
0.016062124 |
-1.794197020 |
36 |
309.15 |
0.003234676 |
10.78 |
1.078E-08 |
0.014965402 |
-1.824911618 |
37 |
310.15 |
0.003224246 |
13.64 |
1.364E-08 |
0.018935815 |
-1.722716008 |
38 |
311.15 |
0.003213884 |
14.84 |
1.484E-08 |
0.020601722 |
-1.686096478 |
39 |
312.15 |
0.003203588 |
18.39 |
1.839E-08 |
0.025530031 |
-1.592948649 |
40 |
313.15 |
0.003193358 |
20.03 |
2.003E-08 |
0.027806772 |
-1.555849429 |
41 |
314.15 |
0.003183193 |
24.32 |
2.432E-08 |
0.033762391 |
-1.471566808 |
42 |
315.15 |
0.003173092 |
27.18 |
2.718E-08 |
0.037732803 |
-1.423280926 |
43 |
316.15 |
0.003163056 |
32.38 |
3.238E-08 |
0.044951736 |
-1.347253534 |
44 |
317.15 |
0.003153082 |
35.36 |
3.536E-08 |
0.049088739 |
-1.309018122 |
45 |
318.15 |
0.003143171 |
42.23 |
4.223E-08 |
0.058626059 |
-1.231909297 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 5 gives the following statistical data using an unweighted least squares treatment.
Slope: -5.92 x 103
Standard error in slope: 236
Intercept: 17.4
Standard error in intercept: 0.753
The results obtained indicate the following vapour pressure relationship: Log10 (Vp (Pa)) = -5.92 x 103/temp (K) + 17.4
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.49.
Run 6
Table 5 – Run 6 Vapour Pressure Data
Temperature (ºC) |
Temperature (K) |
Reciprocal Temperature (K-1) |
Mass Difference(µg) |
Mass Difference(kg) |
Vapor Pressure(Pa) |
Log10Vp |
35 |
308.15 |
0.003245173 |
10.62 |
1.062E-08 |
0.014743281 |
-1.831405862 |
36 |
309.15 |
0.003234676 |
12.50 |
1.250E-08 |
0.017353202 |
-1.760620366 |
37 |
310.15 |
0.003224246 |
13.35 |
1.335E-08 |
0.018533220 |
-1.732049113 |
38 |
311.15 |
0.003213884 |
15.83 |
1.583E-08 |
0.021976096 |
-1.658049464 |
39 |
312.15 |
0.003203588 |
16.50 |
1.650E-08 |
0.022906227 |
-1.640046435 |
40 |
313.15 |
0.003193358 |
20.20 |
2.020E-08 |
0.028042775 |
-1.552179009 |
41 |
314.15 |
0.003183193 |
24.01 |
2.401E-08 |
0.033332031 |
-1.477138219 |
42 |
315.15 |
0.003173092 |
28.47 |
2.847E-08 |
0.039523654 |
-1.403142912 |
43 |
316.15 |
0.003163056 |
32.79 |
3.279E-08 |
0.045520921 |
-1.341788962 |
44 |
317.15 |
0.003153082 |
37.30 |
3.730E-08 |
0.051781956 |
-1.285821547 |
45 |
318.15 |
0.003143171 |
41.99 |
4.199E-08 |
0.058292878 |
-1.234384504 |
A plot of Log10 (vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 6 gives the following statistical data using an unweighted least squares treatment.
Slope: -5.99 x 103
Standard error in slope: 180
Intercept: 17.6
Standard error in intercept: 0.575
The results obtained indicate the following vapour pressure relationship: Log10 (Vp (Pa)) = -5.99x 103/temp (K) + 17.6
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -2.50.
Applicant's summary and conclusion
- Conclusions:
- The vapour pressure of the test item has been determined to be 3.2 x 10-3 Pa at 25 °C using the vapour pressure balance method.
- Executive summary:
Introduction
The vapour presure of trimethylolethane was determined using a procedure designed to be compatible with Method A4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Method
The vapour pressure was determined using a vapour pressure balance. The temperature of the sample was controlled electronically. The mass and temperature readings were recorded automatically into a computer file.
Conclusion
The vapour pressure of the trimethylolethane has been determined to be less than 3.2 x 10-3 Pa at 25 ºC using the vapour pressure balance method.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
