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EC number: 219-956-7
CAS number: 2582-30-1
Groups of 10 male Wistar rats received single oral doses (3100 or
5000 mg/kg bw) of aminoguanidinium hydrogen carbonate dissolved in water
and were observed for 14 days. Rats dosed with 3100 mg/kg bw tolerated
the treatment without clinical signs or mortality. All 10 rats dosed
with 5000 mg/kg bw showed sedation and poor general condition within 2
to 6 days after application of aminoguanidinium hydrogen carbonate, 4/10
died. Thus the LD50(oral) is >5000 mg/kg bw.
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