Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
other: secondary citation
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary citation

Data source

Reference
Reference Type:
secondary source
Title:
Potential Health Hazards of Existing Chemicals: Aminoguanidine bicarbonate
Author:
Duffy PE, Defebdini R, Kremzner LT 1971 (cited in Toxicological Evaluations 15)
Year:
1999
Bibliographic source:
Toxicological Evaluations 15, 417-431, Springer Verlag

Materials and methods

Type of study / information:
in vitro investigation
Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The incubation of menignoma cells with 10^(-4) M aminoguanidinium hydrogen carbonate caused an increase in the cell growth rate, changes in cell morphology and a change in growth pattern.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Aminoguanidinium hydrogen carbonate
EC Number:
219-956-7
EC Name:
Aminoguanidinium hydrogen carbonate
Cas Number:
2582-30-1
Molecular formula:
CH6N4.CH2O3
IUPAC Name:
carbamimidoyldiazanium hydrogen carbonate
Test material form:
other: solid
Details on test material:
no details

Results and discussion

Any other information on results incl. tables

The incubation of menignoma cells with 10^(-4) M aminoguanidinium hydrogen carbonate caused an increase in the cell growth rate, changes in cell morphology and a change in growth pattern.

Applicant's summary and conclusion