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Physical & Chemical properties

Water solubility

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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
11 April 1994 - 27 January 1995
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted according to Method A6 of the Commission Directive 92/69/EEC and in accordance with GLP. Study material is well characterised. Done under GLP and OECD method.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995
Report date:
1995

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes
Type of method:
flask method
Remarks:
Flask stirring method

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
414-490-2
EC Name:
-
Cas Number:
154212-59-6
Molecular formula:
C11H9ClN2O5S
IUPAC Name:
4-nitrophenyl 1,3-thiazol-5-ylmethylcarbonate hydrochloride

Results and discussion

Water solubility
Water solubility:
0.3 g/L
Temp.:
20 °C
pH:
> 1.59 - < 1.63
Remarks on result:
other: +/- 0.5 degrees Celcius
Details on results:
The water solubility determined by the bottle method at the temperature of 23ºC ± 1ºC is:
 
44.11 g/l or 44.11 mg/ml (44110 mg/l)
 
-- and the repeatability of these tests is 0.06% (it must be lower than 15%)

Any other information on results incl. tables

Water solubility was determined by HPLC to be 0.30 g/L at 20 degrees Celcius.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
Water solubility determined to be 0.30 g/L (304 mg/l) at 20 degrees Celcius, making it moderately soluble in water.

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