Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable source. Study performed with acceptable restrictions.

Data source

Reference
Reference Type:
publication
Title:
The acute Oral Toxicity, Repellency, and Hazard Potential of 998 Chemicals to One or More Species of Wild and Domestic Birds.
Author:
Schafer, E. W. et al.
Year:
1983
Bibliographic source:
Arch. Environm. Contam. Toxicol. 12, 355 - 382 (1983)

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-chloroaniline
EC Number:
203-581-0
EC Name:
3-chloroaniline
Cas Number:
108-42-9
Molecular formula:
C6H6ClN
IUPAC Name:
3-chloroaniline
Test material form:
other: liquid
Details on test material:
- Purity not reported
- Empirical formula: C6H6ClN
- Molecular mass: 127.58 g/mole
Dose method:
gavage

Test organisms

Test organisms (species):
other: Redwiged blackbird, Starling and Coturnix

Results and discussion

Effect levelsopen allclose all
Duration (if not single dose):
2 wk
Dose descriptor:
other: R50
Effect level:
> 1 other: %
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Redwinged blackbird
Duration (if not single dose):
2 wk
Dose descriptor:
LD50
Effect level:
> 1 000 other: mg/kg
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Starling
Duration (if not single dose):
2 wk
Dose descriptor:
LD50
Effect level:
422 other: mg/kg
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Coturnix
Repellency factors (if applicable):
Redwinged blackbird: R50 = > 76.9 mg/kg
Further details on results:
The test period was during to 2 - 6 weeks for all species.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The acute oral toxicity of birds were determined to three species during from 2 to 6 weeks. The redwinged blackbird showed a R50 (repellency) of >1.00 % or > 76.9 mg/kg. The starling showed a LD50 of > 1000 mg/kg and the coturnix a LD50 of 422 mg/kg.
Executive summary:

The acute oral toxicity of birds were determined to three species during from 2 to 6 weeks. The redwinged blackbird showed a R50 (repellency) of >1.00 % or > 76.9 mg/kg. The starling showed a LD50 of > 1000 mg/kg and the coturnix a LD50 of 422 mg/k