Registration Dossier
Registration Dossier
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EC number: 203-581-0 | CAS number: 108-42-9
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: secondary literature
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Toxicometric parameters of industrial toxic chemicals under single exposure
- Author:
- Izmerov NF, Sanotsky IV, Sidorov KK
- Year:
- 1 982
- Bibliographic source:
- Centre of International Projects GKNT Moscow 1982 - English-language edition UNEP
Materials and methods
- Principles of method if other than guideline:
- Determination of LC50 in mice after inhalation
- GLP compliance:
- no
- Test type:
- other: no data
Test material
- Reference substance name:
- 3-chloroaniline
- EC Number:
- 203-581-0
- EC Name:
- 3-chloroaniline
- Cas Number:
- 108-42-9
- Molecular formula:
- C6H6ClN
- IUPAC Name:
- 3-chloroaniline
- Reference substance name:
- m-chloroaniline
- IUPAC Name:
- m-chloroaniline
- Test material form:
- other: liquid
- Details on test material:
- no data
Constituent 1
Constituent 2
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 4 h
- Concentrations:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 550 mg/m³ air
- Based on:
- not specified
- Exp. duration:
- 4 h
Any other information on results incl. tables
no data
Applicant's summary and conclusion
- Executive summary:
The inhalation LC50(mouse) of m-chloroaniline is 550 mg/m³
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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