Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

In a reliable and GLP guideline study, the substance 3,6,9,12 -tetraoxotridecan-1 -ol (tetraethylene glycol methyl ether) showed no evidence of mutagenicity in a bacterial reverse mutation (Ames) assay in Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537 and Escherichia coli strain WP2uvra, with or without metabolic activation.

Based on data from category members and supported by a reliable QSAR, this substance is expected to produce the following results from other standard assays:

Bacterial reverse mutation: negative

Cytogenicity study: negative
In vitro mammalian cell gene mutation: negative

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

There is no indication of mutagenic or genotoxic potential. Classification is not required.