Registration Dossier
Registration Dossier
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EC number: 245-883-5 | CAS number: 23783-42-8
Long-term toxicity to fish
Administrative data
- Endpoint:
- long-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Data source
Reference
- Reference Type:
- other: QSAR
- Title:
- ECOSAR v1.11
- Author:
- US EPA
- Year:
- 2 013
- Bibliographic source:
- https://www.epa.gov/tsca-screening-tools/ecological-structure-activity-relationships-program-ecosar-whats-new-v20
Materials and methods
- Principles of method if other than guideline:
- QSAR method
- GLP compliance:
- no
- Remarks:
- not applicable
Test material
- Reference substance name:
- 3,6,9,12-tetraoxotridecanol
- EC Number:
- 245-883-5
- EC Name:
- 3,6,9,12-tetraoxotridecanol
- Cas Number:
- 23783-42-8
- Molecular formula:
- C9H20O5
- IUPAC Name:
- 2,5,8,11-tetraoxatridecan-13-ol
- Test material form:
- liquid
- Details on test material:
- - Physical state: colorless liquid
Constituent 1
Test organisms
- Test organisms (species):
- not specified
- Details on test organisms:
- fish species not specified in model
Study design
- Test type:
- other: QSAR model
- Water media type:
- freshwater
- Total exposure duration:
- 30 d
Results and discussion
Effect concentrations
- Duration:
- 30 d
- Dose descriptor:
- other: ChV value
- Effect conc.:
- 25 g/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Remarks on result:
- ChV (chronic value, QSAR)
Applicant's summary and conclusion
- Executive summary:
A reliable QSAR model estimates that the 30 day NOEC for fish (chronic toxicity) will be 11482mg/l. The model also indicates that with increasing numbers of ethylene oxide units in the molecule, the toxicity further decreases.
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