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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

TetraEGME: Daphnia magna 48hr (TetraEGME) EC50: 22900mg/l

TEGME: Daphnia magna, 48hr values: EC0>500mg/l

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
22 900 mg/L

Additional information

Measured data for the substance tetraethylene glycol methyl ether (TetraEGME) established that the EC50 was around 22900mg/l. A limit dose study using the substance 2 -(2 -(2 -methoxyethoxy)ethoxy ethanol (TEGME or triethylene glycol methyl ether) established that the EC0 was in excess of the maximum tested dose of 500mg/L. A QSAR model predicts that with increasing numbers of ethylene oxide units in the molecule, the toxicity decreases. There is no data availalble on marine invertebrates.