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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Substance TetraEGME, measured data (Pimephales promelas)

LD0 (96hr) >10g/L, >20g/L

LD50 (96hr), <40g/L

Zebrafish embryotoxicity. EC0>2g/L

Substance: 2-(2-(2-methoxyethoxy)ethoxy)ethanol:
Leuciscus idus: 96hr LC0>10000mg/l

Zebrafish embryotoxicity. EC0>0.8g/L

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
20 000 mg/L

Additional information

Experimental studies are available for the tri and tetramethyl glycol ethers (2 -(2 -(2 -methoxyethoxy)ethoxy)ethanol and tetramethyl glycol). These studies show that the substance is effectively non toxic to fish with LC0 values above 20000mg/l. A QSAR confirms this and also shows that with increasing numbers of ethylene oxide units in the molecule, the toxicity further decreases. There is no data available on marine fish.