Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 206-466-3 | CAS number: 345-92-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
Inhalation: If inhaled remove to fresh air. If not breathing give artificail respiration. If breathing is difficult give oxygen.
Skin: In case of contact, immediately wash skin with soap and copious amounts of water.
Eye: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Fire-fighting measures
Extinguishing media: Water fog, alcohol foam, dry chemical, CO2, dry sand.
Unsuitable media: Water jet.
Special Risks: 4,4'-difluorobenzophenone does not ignite easily, however it may burn, producing irritating and poisonous gases. Fine dust dispersed in air in sufficient concentrations and in the presence of an ignition source, is a potential dust explosion hazard.
Special Protective Equipment for Firefighters: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures: Evacuate immediate area. Warn personnel of fire, explosion and health hazard. Remove all sources of ignition. Wear self contained breathing apparatus, rubber boots and heavy rubber gloves.
Environmental Precautions: Warn people in the neighbourhood as necessary. Do not let this chemical enter the environment. Do not flush into sewer, river or any body of water.
Methods and Materials for Containment and Clean-Up: Use non-sparking tools and equipment. Vacuum or sweep up material and place in a disposal container. Avoid runoff to sewers or waterways.
Handling and storage
Handling: Keep away from heat, sparks and flame. Use only with adequate ventilation. Use expolosion proof electrical equipment. Take precautions against build up of electrostatic charges.
Avoid contact with eye, skin and clothing. Wear appropriate personal protective equipment. Provide hand and eye wash stationsnear work area. Wash thoroughly after handling.
Ventilation Reguirements: Use only under local exhaust or general ventilation.
Storage: Keep away from heat flame and all sources of ignition. Keep container tightly closed. Store in a cool dry place.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- bis(4-fluorophenyl) ketone
- Language:
- English
- Labels:
- Class 9 Hazard
Environmentally hazardous substance mark
Special provisions / remarks
- Special provisions:
- 274.335,601
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- bis(4-fluorophenyl) ketone
- Language:
- English
- Labels:
- Class 9 Hazard
Environmentally hazardous substance mark
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- bis(4-fluorophenyl) ketone
- Labels:
- Class 9 Hazard
Environmentally hazardous substance mark
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- bis(4-fluorophenyl) ketone
- Labels:
- Class 9 Hazard
Environmentally hazardous substance mark
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Engineering controls: Safety shower and eye bath. Mechanical exhaust required.
General hygiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.
Personal Protective Equipment: Respiratory protection: Use respirators andcomponents tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator.
Hand protection: Suitable gloves.
Eye protection: Chemical safety goggles
Stability and reactivity
Stability: Materiasl to avoid: Strong oxidising agents, Strong reducing agents.
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, Hydrogen fluoride.
Disposal considerations
Waste from residues: Whatever cannot be saved for recovery may be burned in an approved incinerator or disposed in an approved waste facility. Ensure compliance with local, state and national requirements.
Contaminated Packaging: Empty the container completely before disposal.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
