Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

According to a Mackay Level I model calculation, the main target compartment for bis(4-fluorophenyl) ketone will be the hydrosphere (70 %), followed by sediment and soil (13 % each). The calculated Henry’s Law constant of 0.12 Pa m³/mol at 20 °C indicates low volatility of bis(4-fluorophenyl) ketone from surface waters. The adsorption / desorption behaviour as studied with the batch equilibrium method indicates a very low potential of 3-cyano-3,5,5-trimethylcyclohexanone for sorption to soil or sediment organic matter (Blume scale).


The QSAR calculated rate constant for the OH sensitized photodegradation of bis(4-fluorophenyl) ketone is approximately 4.45E-12 cm3/(molecule * s) (AopWin Computer Program, Vers. 1.92, integrated in U.S. EPA's EPI program Vers. 3.20). At 500,000 OH radicals / cm3 (approximate 24-hour mean in central), this corresponds to a half-life of 3.6 days. Bis(4-fluorophenyl) ketone was not found readily biodegradable in an OECD TG 301 F study.