Registration Dossier
Registration Dossier
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EC number: 216-032-5 | CAS number: 1477-55-0
Endpoint summary
Administrative data
Description of key information
Corrosive substance classified as Packing grade II defined in the recommendations of the United Nations.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
According to Directive 67/548/EEC, when a substance is classified as corrosive and assigned R34, the risk of severe damage to eyes is considered implicit. Data are also available to indicate that the mechanism of respiratory toxicity is corrosivity, and the substance will be labelled as EUH071: ‘corrosive to the respiratory tract’.
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Effects on respiratory irritation: highly irritating
Justification for classification or non-classification
The test substance causes visible necrosis through the epidermis and into the dermis of rat and mouse skin after application of the test substance for between 3 minutes and 1 hour. It is therefore classified as R34: causes burns under the criteria of Directive 67/548/EEC and Corrosive category 1B under GHS as reflected by Regulation (EC) 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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