Registration Dossier
Registration Dossier
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EC number: 216-032-5 | CAS number: 1477-55-0
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- No data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature cited in SIDS dossier, experimental data not retained by Japanese Ministry of Economy Trade and Industry
Data source
Reference
- Reference Type:
- secondary source
- Title:
- m-phenylenebis(methylamine)
- Author:
- OECD SIDS
- Year:
- 2 001
- Bibliographic source:
- http://www.inchem.org/documents/sids/sids/aminomethylb.pdf [accessed 22 June 2010]
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- m-phenylenebis(methylamine)
- EC Number:
- 216-032-5
- EC Name:
- m-phenylenebis(methylamine)
- Cas Number:
- 1477-55-0
- Molecular formula:
- C8H12N2
- IUPAC Name:
- 1-[3-(aminomethyl)phenyl]methanamine
- Test material form:
- liquid
- Details on test material:
- - Name of test material (as cited in study report): m-xylylenediamine
- Physical state: Transparant, colourless liquid
- Melting point: 13 degrees Centigrade
- Density: 1.052
- Solubility in water: Above 300 ppm
- Solubility in methanol: Above 300 ppm
- Solubility in chloroform: Above 300 ppm
- Solubility in hexane: Above 300 ppm
Constituent 1
- Radiolabelling:
- not specified
Sampling and analysis
- Details on sampling:
- No data
Test solutions
- Vehicle:
- not specified
- Details on preparation of test solutions, spiked fish food or sediment:
- No data
Test organisms
- Test organisms (species):
- Cyprinus carpio
- Details on test organisms:
- No data
Study design
- Route of exposure:
- other: No data
- Test type:
- not specified
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 42 d
Test conditions
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- TOC:
- No data
- Salinity:
- No data
- Details on test conditions:
- Flow rate of test water: 582 L/day
- Nominal and measured concentrations:
- Dose level 1: 2mg/L
Dose level 2: 0.2 mg/L - Reference substance (positive control):
- not specified
- Details on estimation of bioconcentration:
- No data
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- < 0.3 dimensionless
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:2mg/L
- Type:
- BCF
- Value:
- < 2.7 dimensionless
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:0.2 mg/L
- Details on kinetic parameters:
- No data
- Metabolites:
- No data
- Results with reference substance (positive control):
- No data
- Details on results:
- No data
- Reported statistics:
- No data
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The substance does not bioaccumulate
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