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Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Testing was conducted between 2009-07-30 and 2009-08-20
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
BS4633
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Date of Inspection 2008-08-19; Date of Signature 2009-03-04
Type of method:
method to determine freezing temperature
Remarks:
Method for the determination of crystallizing point
Melting / freezing pt.:
287.15 K
Decomposition:
no
Sublimation:
no

Cooling data for Determinations 1 and 2 are shown in the following tables:

 

Determination 1

Time(s)

Temperature (K)

Time(s)

Temperature (K)

0

292.65

690

283.65

30

291.65

720

284.15

60

291.15

750

284.65

90

290.65

780

286.65

120

290.15

810

287.15

150

289.65

840

287.15

180

289.15

870

287.15

210

288.65

900

287.15

240

288.15

930

287.15

270

287.65

960

287.15

300

287.15

990

287.15

330

286.65

1020

287.15

360

286.65

1050

287.15

390

286.15

1080

287.15

420

286.15

1110

287.15

450

286.15

1140

287.15

480

285.15

1170

287.15

510

285.15

1200

287.15

540

284.65

1230

287.15

570

284.15

1260

287.15

600

284.15

1290

287.15

630

283.65

1320

287.15

660

283.65

 

 


Determination 2

Time(s)

Temperature (K)

Time(s)

Temperature (K)

0

298.15

630

289.65

30

297.15

660

289.65

60

296.15

690

289.15

90

296.15

720

289.15

120

295.15

750

288.65

150

294.15

780

288.65

180

294.15

810

288.15

210

293.65

840

288.15

240

293.15

870

287.65

270

292.65

900

287.65

300

292.15

930

287.15

330

291.65

960

287.15

360

291.15

990

287.15

390

290.15

1020

287.15

420

290.65

1050

287.15

450

290.65

1080

287.15

480

290.65

1110

287.15

510

290.15

1140

287.15

540

290.15

1170

287.15

570

290.15

1200

287.15

600

289.65

1230

287.15

Graphs of temperature (K) versus time (seconds) for Determinations 1 and 2 are shown in Figures 1 and 2 respectively (attached).

In Determination 1 the temperature of the test material was recorded at a minimum of 283.65 K while the test material was still in the liquid state. The temperature then increased to a plateau of 287.15 K where the test material was observed to freeze. This sequence of events shows that the test material had undergone the process of supercooling.

The test material appears not to have undergone supercooling in Determination 2; however both determinations recorded a plataeu temperature of 287.65 K where the test material was observed to freeze.

Conclusions:
The freezing point of the test material has been determined to be 287.15 ± 0.5 K

Description of key information

GLP guideline study quoting melting/freezing point as 287.15 ± 0.5 K (OECD 102)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
14 °C

Additional information

Result equates to a melting/freezing point of 14 °C