Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 249-694-9 | CAS number: 29556-33-0
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26/5/2016-27/6/2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- Experimental test result performed using standard OECD test guidelines.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: refer below principle
- Principles of method if other than guideline:
- The particle size distribution of test item 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-1,3-dimethyl-1H-benzimidazolium chlorine (CAS No. 29556-33-0) was determined by granulometric analysis with rotap sieve shaker.
- GLP compliance:
- no
- Type of method:
- sieving
- Type of particle tested:
- primary particle
- Type of distribution:
- counted distribution
Test material
- Reference substance name:
- 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]-1,3-dimethyl-1H-benzimidazolium chloride
- EC Number:
- 249-694-9
- EC Name:
- 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]-1,3-dimethyl-1H-benzimidazolium chloride
- Cas Number:
- 29556-33-0
- Molecular formula:
- C22H24N3O2.Cl
- IUPAC Name:
- 2-[7-(diethylamino)-2-oxo-2H-chromen-3-yl]-1,3-dimethyl-2,3-dihydro-1H-3,1-benzimidazol-1-ium chloride
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study report): 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]-1,3-dimethyl-1H-benzimidazolium chloride
- Molecular formula: C22H24N3O2.Cl
- Molecular weight: 397.904 g/mol
- Smiles notation: c1([n+](c2c(n1C)cccc2)C)c1c(oc2c(c1)ccc(c2)N(CC)CC)=O.[ClH-]
- InChl: 1S/C22H24N3O2.ClH/c1-5-25(6-2)16-12-11-15-13-17(22(26)27-20(15)14-16)21-23(3)18-9-7-8-10-19(18)24(21)4;/h7-14H,5-6H2,1-4H3;1H/q+1;/p-1
- Substance type: Organic
- Physical state: Solid
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]-1,3-dimethyl-1H-benzimidazolium chloride
- Molecular formula (if other than submission substance): C22H24N3O2.Cl
- Molecular weight (if other than submission substance): 347.4159
- Smiles notation (if other than submission substance): c1(c2c(oc3c(c2)ccc(N(CC)CC)c3)=O)nc2ccccc2n1C
- InChl (if other than submission substance): 1S/C21H21N3O2/c1-4-24(5-2)15-11-10-14-12-16(21(25)26-19(14)13-15)20-22-17-8-6-7-9-18(17)23(20)3/h6-13H,4-5H2,1-3H3
- Substance type: Organic
- Physical state: Solid
Results and discussion
Particle size
- Key result
- Percentile:
- D50
- Remarks on result:
- other: 'Mass median diameter'
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- 150 µm
- Distribution:
- 30 %
- No.:
- #2
- Size:
- 106 µm
- Distribution:
- 19.84 %
- No.:
- #3
- Size:
- 75 µm
- Distribution:
- 10.02 %
- No.:
- #4
- Size:
- 53 µm
- Distribution:
- 19.18 %
- No.:
- #5
- Size:
- 25 µm
- Distribution:
- 12.01 %
- No.:
- #6
- Size:
- 10 µm
- Distribution:
- 6.81 %
Any other information on results incl. tables
OBSERVATION TABLE:
Amount of test item weighed (g) = 10 g
Method run time (min) = 10min
Sieve sizes(in microns) |
Weight of petridishes (g) |
Weight of petridishes + test item (g) |
Test item quantity retained after sieving (g) |
Percentage (%) of test item* |
150 microns |
37.115 |
40.192 |
3.000 |
30.00% |
106 microns |
40.121 |
42.105 |
1.984 |
19.84% |
75 microns |
38.900 |
39.902 |
1.002 |
10.02% |
53 microns |
36.582 |
38.500 |
1.918 |
19.18% |
25 microns |
37.892 |
39.093 |
1.201 |
12.01% |
10 microns |
41.201 |
41.882 |
0.681 |
6.81% |
*Percentage of test item= test item retained after sievingX 100
Original test itemtaken
Applicant's summary and conclusion
- Conclusions:
- The particle size distribution of test item 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-1,3-dimethyl-1H-benzimidazolium chlorine (CAS No. 29556-33-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was found to be in the range of 150 micron to 10 micron.
- Executive summary:
The particle size distribution of test item 2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-1,3-dimethyl-1H-benzimidazolium chlorine (CAS No. 29556-33-0) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was found to be in the range of 150 micron to 10 micron.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
