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Physical & Chemical properties

Partition coefficient

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Description of key information

The partition coefficient log Pow of the test substance was determined to be log Pow = 2.59 at 23 °C.

Key value for chemical safety assessment

Log Kow (Log Pow):
2.59
at the temperature of:
23 °C

Additional information

A study was conducted in accordance with OECD TG 117 and Regulation (EC) No 440/2008 method A.8 to determine the partition coefficient of the test substance. Using the HPLC method partition coefficient Pow was determined in two individual measurements. A calibration function (log K versus log Pow, linear fit) was determined using the literature values for Pow of the reference items and the retention times in the six determinations. The coefficient of determination r2 of the calibration function log K/Log Pow was calculated to be 0.9742 and 0.9739 respectively which were regarded to be sufficient to use. The retention time of the test item lied within the range of the reference items. Thus, all validation criteria ere fulfilled and no observations were made which might cause doubts concerning the validity of the study outcome. The log Pow of the test substance was determined to be 2.59 at 23 °C.