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Diss Factsheets
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EC number: 203-868-0 | CAS number: 111-42-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Earthworm reproduction (no. of progeny): 63-d EC50 = 776 mg/kg soil dw
Earthworm adult survival: 35-d LC50 > 1000 mg/kg soil dw
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 776 mg/kg soil dw
Additional information
In accordance with REACH Regulation (EC) 1907/2006, Annex IX and X, Section 9.4., Colum 2, the toxicity testing to terrestrial organisms shall be proposed depending on the results of the chemical safety assessment. According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the criteria for classification as hazardous according to Regulation EC 1272/2008 and its second adaptation 286/2011 or is assessed to be a PBT or vPvB. The hazard assessment of diethanolamine reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment.
In addition, indirect exposure to soil is unlikely since the substance is readily biodegradable according to OECD criteria. For substances being considered as „readily biodegradable“, it can be assumed that they will be completely biologically degraded within the STP process. Indirect exposure to soil is not likely e.g. via agricultural use of sewage sludge since diethanolamine is readily biodegradable (see IUCLIC Ch. 5.2.1, BASF AG, 1992). Furthermore, for substances not passing the STP-process but being readily biodegradable, it can be assumed that they will be also biological degraded in the surface water within a short time. Direct exposure to soil is not likely, since the substance is not intentionally applied to soil. The substance has no potential to bioaccumulate (BCF = 2.7 L/kg considering all mitigating factors (9.2 L/kg not considering any mitigating factors), according to the BCF baseline model v.04.11 implemented in OASIS Catalogic v5.14.1.5, (BASF SE, 2021). Regarding the charged molecule at pH 7 the log Koc was estimated to be 0.99 (Koc = 10 L/kg) following the method of Franco & Trapp, 2008, 2009, 2010 (BASF, 2021). Therefore, adsorption to solid soil phase is not expected (log Koc < 3).
In conclusion no testing is required. The predicted no effect concentration (PNEC) for soil was derived by applying an assessment factor of 1000 to the lowest EC50 according to REACH Guidance R.10.6.2 as results are available from short-term tests with a producer, a consumer and a decomposer.
Assessment
However, a chronic earthworm test was performed according to a guideline by Environment Canada (PTAC, 2006). The test species was Eisenia andrei. A series of 8 test item concentrations was tested (125 - 8000 mg/kg soil dw) in addition to a control. Analytical monitoring was performed. The recovery was poor (<= 28%), which is probably due to an insufficient analytical method; however, for earthworm testing analytical monitoring is not required according to OECD 222. After 35 d the adult survival was measured. After 63 d the effects on reproduction were determined (number of progeny, wet and dry mass of individual progeny). The report only contains EC25 and EC50 values; therefore the results are considered as acute effect values. The assessment is based on those endpoints which are considered in the relevant OECD 222 guideline (adult survival and number of progeny). The 35-d LC50 (adult survival) was 4141 mg/kg soil dw. The EC50 for reproduction (no. of progeny) was 776 mg/kg soil dw and the EC25 171 mg/kg soil dw.
The PNEC soil was derived based on experimental data only according to REACH Guidance R.10.6.2 as short-term data are available for producer, consumer, and decomposer.
Therefore, no additional tests on macroorganisms are provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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