Registration Dossier
Registration Dossier
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EC number: 809-896-5 | CAS number: 60435-70-3
Endpoint summary
Administrative data
Description of key information
Additional information
Short term toxicity
Measured data for 2-methyl-1-heptanol are not available. In order to reduce animal testing, read-across is proposed to fulfil REACH Annex VII-X requirements for the registered substance from substances that have similar structure and physicochemical properties. Aquatic ecotoxicity data are read-across from a structural analogue, the linear isomer octan-1-ol, in the context of the Category data set (discussed in the CSR). Reliable acute toxicity tests results with octan-1-ol are available for freshwater fish (Pimephales promelas), invertebrates (Daphnia magna) and algae (Pseudokirchnerella subcapitata). LC50 or EC50 values for the three organisms were 13.3, 20 and 14 mg/L respectively.
In waste-water treatment plant micro-organisms, octan-1-ol does not cause inhibition at the limit of water solubility. In view of the ready biodegradability, further information is not required in REACH.
Long term toxicity
A reliable 21 day reproduction NOEC value of 1.0 mg/L has been determined for the effects of octan-1-ol on reproduction and survival of the freshwater test organism Daphnia magna.
In accordance with Column 2 of REACH Annex IX, the long-term aquatic toxicity to fish study (required in Section 9.1.6) does not need to be conducted as the chemical safety assessment according to Annex I indicates that this is not necessary.
In accordance with Column 2 of REACH Annex X, long-term toxicity testing with sediment organisms (required in Section 9.5.1) is not needed as the chemical safety assessment according to Annex I indicates that this is not necessary.
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