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EC number: 231-635-3 | CAS number: 7664-41-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
Link to relevant study record(s)
- Endpoint:
- sediment toxicity: long-term
- Type of information:
- other: Assessment of SNIFFER
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Principles of method if other than guideline:
- not relevant since statement in report
- GLP compliance:
- no
- Dose descriptor:
- other: see remarks on results
- Nominal / measured:
- not specified
- Conc. based on:
- other: not relevant
- Basis for effect:
- other: see remarks on results
- Remarks on result:
- not measured/tested
- Remarks:
- The presented values are NOT relevant for the risk assessment. The publication contains a statement (see below) but does not provide further information. However, using IUCLID 6.5.15 (most recent version at dossier preparation), the CSR generator does not work without having the entries populated. Therefore dummy information was added.
- Details on results:
- Ammonia does not accumulate in sediments and the derivation of sediment PNECs for the protection of benthic organisms is not required. Given the high water solubility of ammonia, bioaccumulation is not considered important.
- Executive summary:
Ammonia does not accumulate in sediments and the derivation of sediment PNECs for the protection of benthic organisms is not required. Given the high water solubility of ammonia, bioaccumulation is not considered important.
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- see read across justification
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 1.9 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- act. ingr.
- Remarks:
- NH3
- Basis for effect:
- mortality
- Details on results:
- Since the result was reported based on NH3, no conversion is needed for read across.
- Executive summary:
The 96 hour toxicity of ammonium chloride to the sediment dwelling cladoceran Chydorus sphaericus was determined in a sediment-free system. The LC50 was reported based on the NH3 concentration. The 96 hour LC50 was 1.9 mg NH3/L.
Since the result was reported based on NH3, no conversion is needed for read across.
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Four species of marine or estuarine amphipods (Rhepoxynius abronius, Eohaustorius estuarius, Ampelisca abdita and Grandidierella japonica) were exposed to ammonia in seawater, in the absence of sediment, under controlled laboratory conditions, to determine the concentrations of ammonia that would be acutely toxic to those species.
- GLP compliance:
- no
- Water media type:
- saltwater
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.83 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Remarks:
- NH3
- Basis for effect:
- mortality
- Remarks on result:
- other: A. abdita (was found to be the most sensitive to ammonia)
- Details on results:
- A. abdita was found to be the most sensitive to ammonia, with a median lethal concentration (LC50) of 49.8 mg/liter total ammonia (0.83 mg/liter as un-ionized ammonia). R. abronius was also relatively sensitive: LC50 = 78.7 mg/liter total ammonia (1.59 mg/liter un-ionized ammonia). E. estuarius and G. japonica were less sensitive, with estimated LC50 values of 125.5 mg/liter and 148.3 mg/liter total ammonia, respectively (2.49 mg/liter and 3.35 mg/liter un-ionized ammonia). The absence of sediment did not appear to influence the response of the amphipods over the 96-h exposure period.
- Executive summary:
A. abdita was found to be the most sensitive to ammonia, with a median lethal concentration (LC50) of 49.8 mg/liter total ammonia (0.83 mg/liter as un-ionized ammonia). R. abronius was also relatively sensitive: LC50 = 78.7 mg/liter total ammonia (1.59 mg/liter un-ionized ammonia). E. estuarius and G. japonica were less sensitive, with estimated LC50 values of 125.5 mg/liter and 148.3 mg/liter total ammonia, respectively (2.49 mg/liter and 3.35 mg/liter un-ionized ammonia). The absence of sediment did not appear to influence the response of the amphipods over the 96-h exposure period.
Referenceopen allclose all
Description of key information
Ammonia does not accumulate in sediments and the derivation of sediment PNECs for the protection of benthic organisms is not required. Given the high water solubility of ammonia, bioaccumulation is not considered important.
Key value for chemical safety assessment
Additional information
Ammonia does not accumulate in sediments and the derivation of sediment PNECs for the protection of benthic organisms is not required. Given the high water solubility of ammonia, bioaccumulation is not considered important. Based on tests without sediment, sediment dwellers were not more sensitive than pelagic organisms.
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