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Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
see read across justification
Reason / purpose for cross-reference:
read-across source
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.79 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
other: non-ionised ammonia-N
Basis for effect:
mortality
Remarks:
and reproduction
Details on results:
Survival was slightly less at the two highest test concentrations (73%) than at the other treatments (86-100%) but were not significantly different from the control. Daphnid growth (determined by length) was significantly reduced at the higher test concentration of 1.3 mg/L NH3-N. Mean length for the control and the high concentration were 3.52 and 3.02 mm respectively. Reproduction was also affected. The first young were produced on day 7 of the test in all treatments except the highest concentration, where no young were found until day 9. The average number of young/adult was significantly lower at that concentration-6.4 versus 24.6 in the control.

The overall NOEC is 0.79 mg NH3-N/L (measeured).

Applying the converstion factor from NH3-N to NH3, the overall NOEC of 0.79 mg NH3-N/L corresponds to a concentration of 0.961 mg NH3/L.
Executive summary:

The authors investigated the long-term effects of ammonium chloride exposure to Daphnia magna. Survival was slightly less at the two highest test concentrations (73%) than at the other treatments (86-100%) but were not significantly different from the control. Daphnid growth (determined by length) was significantly reduced at the higher test concentration of 1.3 mg/L NH3-N. Mean length for the control and the high concentration were 3.52 and 3.02 mm respectively. Reproduction was also affected. The first young were produced on day 7 of the test in all treatments except the highest concentration, where no young were found until day 9. The average number of young/adult was significantly lower at that concentration-6.4 versus 24.6 in the control.

The overall NOEC is 0.79 mg NH3-N/L (measured).

Applying the converstion factor from NH3-N to NH3, the overall NOEC of 0.79 mg NH3-N/L corresponds to a concentration of 0.961 mg NH3/L.

Description of key information

A NOEC of 0.961 mg/L was identified in a long-term study in Daphnia magna.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
NOEC
Effect concentration:
0.961 mg/L

Additional information

Reinbold & Pescitelli (1990) investigated the long-term effects of ammonium chloride exposure to Daphnia magna. Survival was slightly less at the two highest test concentrations (73%) than at the other treatments (86-100%) but were not significantly different from the control. Daphnid growth (determined by length) was significantly reduced at the higher test concentration of 1.3 mg/L NH3. Mean length for the control and the high concentration were 3.52 and 3.02 mm respectively. Reproduction was also affected. The first young were produced on day 7 of the test in all treatments except the highest concentration, where no young were found until day 9. The average number of young/adult was significantly lower at that concentration-6.4 versus 24.6 in the control.

 

Applying the conversion factor from NH3-N to NH3, the overall NOEC of 0.79 mg NH3-N/L corresponds to a concentration of 0.961 mg NH3/L.