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EC number: 211-746-3 | CAS number: 693-23-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
According to Mackay Level I model calculations, the main target compartment for dodecanedioic acid will be water (79.4 %) followed by sediment (10.3 %) and soil (10.2 %). The air compartment is not expected to be relevant. The calculated Henry’s law constant of 1.15E-7 Pa m3/mol indicates very low volatility of dodecanedioic acid from surface waters. With an experimental (HPLC) Koc of 40 (dissociated) to 79 (undissociated) l/kg, the sorption potential of dodecanedioic acid to soil or sediment organic matter is expected to be very low (Blume scale).
The QSAR calculated rate constant for the OH sensitized photodegradation of dodecanedioic acid is approximately 1.41E-11 cm3/(molecule * s). At 500,000 OH radicals / cm3 (approximate 24-hour mean in central Europe), this corresponds to a half-life of 27.4 hours. Dodecanedioic acid was found readily biodegradable. Biodegradation is expected to be the predominant way of removal from the environment while photolytical or hydrolytical degradation are expected to be of minor importance. The partition coefficient 1-octanol/water of dodecanedioic acid is log Kow = 3.20 at 25 °C, indicating a relevant potential for bioaccumulation. However, additional information particularly on degradability points to an insignificant bioaccumulation potential.
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