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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

No significant concentrations are present in the fresh water and seawater compartment. This is supported by exposure assessment carried out using the ECETOC TRAM, indicating low exposure to the water compartment. Predicted regional PEC and the predicted maximal local PEC in water are very low and indicated no risk for the water compartment, therefore long term long-term toxicity tests with aquatic invertebrates are not needed.

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Additional information

Two long-term studies with Daphnia magna are available. However these studies were not found to be reliable as for one study there were possible problems with infection of the test organisms (Kordel et al., 1984) and for the other it was found that a 21-day test was not possible unless the Daphnia had been treated with streptomycin (Scheubel, 1984). Use of the food supplement could also cause problems as it did not dissolve fully. It is not entirely clear from the report whether the problems described affected the outcome of the tests.