Registration Dossier
Registration Dossier
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EC number: 240-934-8 | CAS number: 16893-85-9
Endpoint summary
Administrative data
Description of key information
Reliable information on acute inhalation toxicity indicates that the substance shall be classified according to in force regulations. Some non-standard acute oral toxicity studies as well as information on structurally related substance are available and are reported. This data also indicates that the substance shall be classified according to in force regulations. Waivers are appropriate for acute dermal toxicity as it is not a relevant exposure route.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 70 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 1 814 mg/m³ air
Additional information
Acute oral toxicity
As quite little information on this substance is available, read-across from structural analogues based on fluorides has been carried out. LD50 values obtained for fluorides are in the range of 44-114 mg/bw. These values obtained for this substance indicate that LD50 value is of 70 mg/bw. As it is within the range of those found for fluorides, this value is used for CSA
Acute inhalation toxicity
A study performed by the registrant in 2010 has clearly shown that LD50 for male and female is 1.841 mg/L. However, symptoms appeared when the animals were doses 0.45 mg/L, having this value been established as LOAEC.
Acute dermal toxicity
Information available on this endpoint does not indicate that the substance does cause any harm. However, as dermal is not considered a relevant route of exposure, a waiver is appropriate for this endpoint.
Justification for classification or non-classification
This substance is classified according to the CLP Regulation (EC) 1272/2008 in Acute Toxicity Category 3 (H301, H311, H331). This classification is consistent with the data reviewed and no change is proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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