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Short-term toxicity to fish

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Description of key information

4-Hydroxy TEMPO was tested for short-term toxicity to fish in a 96 h-semistatic test according to EU-method C.1 and OECD guideline 203. A LC50 of 545 mg/L was assessed.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
545 mg/L

Additional information

In this study the influence of 4-OH TEMPO on zebrafish (Brachidanio rerio) was investigated according to EU-method C.1 and OECD guideline 203. Fish were exposed to the test item for 96 hours under semi-static conditions. The frequency of the renewal periods was daily. The fish were exposed to 125, 200, 350, 550 and 1000 mg/L of test substance. The 96 h LC50 value was determined as 545 mg/L and the 96 h LC100 was determined to be 1000 mg/L.