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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Description of key information

4-Hydroxy TEMPO was tested for toxicity to microorganisms in a 16 hour study on Pseudomonas putida test according to DIN 38412. An EC50 of 890 mg/L and an EC10 of 430 mg/L was assessed.

Key value for chemical safety assessment

EC50 for microorganisms:
890 mg/L
EC10 or NOEC for microorganisms:
430 mg/L

Additional information

The toxicity of 4 -Hydroxy TEMPO to microorganisms was investigated according to DIN 38412, part 8 (Pseudomonas Zellvermehrungshemm-Test). Pseudomonas were exposed to the test item for 16 hours to nominal concentrations of 313, 625, 1250, 2500, 5000 and 10000 mg/L. The EC50 based on growth inhibition was assessed at 890 mg/L. The EC10 was determined at 430 mg/L.