Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dermal absorption, other
Type of information:
other: Collection of data
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1989

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Pentaerithrityl tetranitrate
EC Number:
201-084-3
EC Name:
Pentaerithrityl tetranitrate
Cas Number:
78-11-5
Molecular formula:
C5H8N4O12
IUPAC Name:
3-(nitrooxy)-2,2-bis[(nitrooxy)methyl]propyl nitrate (non-preferred name)

Results and discussion

Applicant's summary and conclusion

Executive summary:

PETN was mixed with acetone and rubbed onto the palm of a human hand; after 1 hour, essentially all of the PETN could be recovered by washing [Von Oettingen et al. (1944)].