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EC number: 201-084-3 | CAS number: 78-11-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- other: Methods for Acute Toxicity Tests with Fish, Macroinvertebrates, and Amphibians (EPA, 1975)
- GLP compliance:
- not specified
- Test organisms (species):
- Daphnia magna
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 24 h
- Hardness:
- 35 mg/1 as CaCO3,
- Test temperature:
- 21+/-1 ºC
- pH:
- 7.1
- Dissolved oxygen:
- >60% of saturation
- Nominal and measured concentrations:
- 9700000 mg/L
- Details on test conditions:
- Confidence interval: 7500000-12600000 g/L
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 292 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 0.25
- Details on results:
- No reported
- Validity criteria fulfilled:
- yes
- Conclusions:
- Not toxic
- Executive summary:
Studies performed on toxicity to Daphnia magna of pentaerythritol tetranitrate at different concentrations show that caused effects are not associated to the substance, but to the high pH of the solution (>12) resulting from desensitization, which is much higher than environmental.
To determine the effect of the high pH, resulting from the desensitization process, of test materials, bioassays were performed with Daphnia magna and Pimephales promelas exposed to neutralized versus unneutralized materials.
Reference
Description of key information
LC50 values obtained from studies performed on toxicity to Daphnia magna of pentaerythritol tetranitrate at different concentrations show that the substance is not toxic. Observed mortality seems to be associated to high pH (>12), resulting from the desensitization process.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 292 mg/L
Additional information
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