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Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation, other
Type of information:
other: Collection of data
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Hydrocarbons and organic nitrogen compound; Patty's Toxicology
Author:
Eula Bingham, Barbara Cohrssen and Charles Powell, Editors
Year:
2005
Bibliographic source:
CD-ROM (2005). NY, NY: John Wiley & Sons

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Pentaerithrityl tetranitrate
EC Number:
201-084-3
EC Name:
Pentaerithrityl tetranitrate
Cas Number:
78-11-5
Molecular formula:
C5H8N4O12
IUPAC Name:
3-(nitrooxy)-2,2-bis[(nitrooxy)methyl]propyl nitrate (non-preferred name)

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Executive summary:

Patch tests in 20 persons gave no evidence of sensitization, although some cases of mild illness and dermatitis have been attributed to contact with the substance in ordnance plants.