Registration Dossier

Diss Factsheets

Toxicological information

Skin sensitisation

Currently viewing:

Administrative data

Endpoint:
skin sensitisation, other
Type of information:
other: Collection of data
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Hydrocarbons and organic nitrogen compound; Patty's Toxicology
Author:
Eula Bingham, Barbara Cohrssen and Charles Powell, Editors
Year:
2005
Bibliographic source:
CD-ROM (2005). NY, NY: John Wiley & Sons

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Pentaerithrityl tetranitrate
EC Number:
201-084-3
EC Name:
Pentaerithrityl tetranitrate
Cas Number:
78-11-5
Molecular formula:
C5H8N4O12
IUPAC Name:
3-(nitrooxy)-2,2-bis[(nitrooxy)methyl]propyl nitrate (non-preferred name)

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Executive summary:

Patch tests in 20 persons gave no evidence of sensitization, although some cases of mild illness and dermatitis have been attributed to contact with the substance in ordnance plants.

Categories Display