Registration Dossier

Administrative data

Description of key information

No reliable studies on acute toxicity are available. Due to explosive properties of the substance, the performance of this test is technically not possible.
However, by common knowledge it is possible to consider that the acute effects of exposure to PETN are similar to those of nitroglycerin. Hypotension and increased respiratory rate may both occur, but to a lesser degree than is observed with nitroglycerin. In contrast to nitroglycerin, little reflex tachycardia is observed with PETN. Dyspnea and convulsions have also been reported.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion

Acute toxicity: via dermal route

Endpoint conclusion

Additional information

Due to explosive properties of the substance, the performance of this test is highly advised against. It should also be considered that the production process of this substance and its reasonable use make highly unlikely any exposure.

Justification for classification or non-classification

No reliable information is available.