Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Dose descriptor:
1 000 mg/kg bw/day
Additional information

A study performed following the guidance USEPA OPPTS 870.3550 Reproduction/Developmental Toxicity Screening Test demostrated that rats (10 male and 10 female) orally dosed 100, 500 and 1000 mg/kg for 56 days did not show any effects on their reproductive performance.

Short description of key information:
Reliable information on toxicity for reproduction shows a NOAEL of > 1000 mg/kg bw/day.

Justification for classification or non-classification

No classification is proposed based on the results obtained from studies performed.