1-phenylethyl acetate

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

9th November 2010 to 30th December 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: A GLP compliant study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Remarks:

Swiss Ordinance on Good Laboratory Practice adopted 18th May 2005 [OGLP, SR 813.112.1]

Specific details on test material used for the study:

- Name of test material (as cited in study report): 1-phenylethyl acetate
- Physical state: colourless to pale yellow liquid
- Name of test material (as cited in study report): Gardenol
- Lot/batch No.: VE00123242
- Expiration date of the lot/batch: 14th January 2013

Boiling pt.:

498 K

Atm. press.:

101.325 kPa

Boiling pt.:

225 °C

Atm. press.:

101.325 kPa

Boiling point determination

First determination: observed boiling point = 223.5 ºC

Second determination: observed boiling point = 222.4 ºC

Correction to normalised pressure

The atmospheric pressure at the time of the experiment was 96.12 kPa (Meteo Suisse). A correction of the temperature to normalised pressure (101.325 kPa) was made. The determination of this corrected factor was made using the Sidney Young equation as recommended in OECD Guideline 103.

Tn = T + (f_T+Δp)

Where:

Δp = 101.325 kPa – p

p = pressure in kPa; the pressure was obtained from the Swiss meteorological service for the time of the experiment.

f_T= rate of change of boiling temperature with pressure in K/kPa, a value of 0.47 K/kPa was used, as published in OECD guideline 103

T = temperature in K

T_n= normal boiling point

Conclusions:

Under the conditions of the test, the boiling point of the test substance was determined to be 498 K (225 ºC).

Executive summary:

In a GLP compliant boiling point study conducted in line with standardised guidelines OECD Guideline 103, EU Method A.2 and EPA OPPTS 830.7220, the boiling point of the test substance was determined using the method according to Siwoloboff. The boiling point of the substance was determined to be 498 (225 ºC) at 101.325 kPa.

Description of key information

The boiling point of 1-phenylethyl acetate was determined to be 448 K (225ºC) at 101.325 kPa according to a study performed in line with OECD Guideline 103, EU Method A.2 and EPA OPPTS 830.7220.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

448 K

Additional information

The key study (Givaudan, 2010) was conducted in line with GLP and standardised guidelines with a sufficient level of detail to assess the quality of the study. The study was performed to a good standard and was assigned a reliability score of 1 in accordance with Klimisch (1997).

The supporting study (JECFA, 2001) contains limited information on materials and methods and results and discussion and was assigned a reliability score of 2 in accordance with Klimisch (1997).