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EC number: 221-416-0 | CAS number: 3088-31-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish
Based on the various studies available with Klimish rating 2 for the target substance CAS NO 3088-31-1 and read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1 |
LC50 |
25 mg/l |
mortality |
96 hrs |
Danio rerio |
Study Report for target chemical |
2 |
LC50 |
102.59 mg/l |
mortality |
96 hrs |
Danio rerio |
Predicted data for target chemical |
3 |
LC50 |
46 mg/l |
mortality |
48 hrs |
Oryzias latipes |
Data from publication for CAS NO 151-21-3 |
By applying weight of evidence approach to the studies summarized in the above table it can be observed that the LC50 values was found to be in range of 25 to 102.59mg/l in 96 hrs and 48 hrs on the basis of mortality effect . But the BCF value ofSodium 2-(2-dodecyloxyethoxy) ethyl sulphatereported was not >= 2000 as well as the substance was found to be rapidly degradable. Thus considering the CLP Criteria for aquatic classification of the substance, it is concluded that Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate does not exhibit short term toxicity to fish (Oryzias latipes,Danio rerio)
Long term toxicity to fish:
Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a static fresh water system, the NOEC value for the substance is estimated to be36.507mg/l for fish for 28 days of exposure duration.Since, the test substance is redialy degradable in aquatic environment, it can be concluded that the test chemical can be considered as non-toxic to fish at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.
Short-term toxicity to aquatic invertebrates
Based on the various studies available with Klimish rating 2 for target chemical CAS NO 3088-31-1 and the read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1 |
LC50 |
86.09 mg/l |
mortality |
48 hrs |
Daphnia magna |
Predicted data for target chemical |
2 |
LC50 |
7.2 - 154 mg/L.
|
mortality |
24 hrs |
Artemia salina |
Data from publication for CAS no 151-21-3 |
3 |
LC50 |
10.9 – 29.4 mg/L.
|
mortality |
24 hrs |
Brachionus plicatilis |
Data from publication for CAS no 151-21-3 |
4 |
LC50 |
5.1 – 84 mg/L.
|
mortality |
24 hrs |
Daphnia magna |
Data from publication for CAS no 151-21-3 |
By applying weight of evidence approach to the studies summarized in the above table it can be observed that LC50 value is expected to be in range of 5.1 to 154 mg/l in a 24 to 48 hrs study on the basis of mortality effect. But the BCF value of Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate reported was not >= 2000 as well as the substance was found to be rapidly degradable. Thus according to CLP criteria of aquatic classification it is concluded that the substance Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate is not toxic to aquatic invertebrate (Daphnia magna, Artemia salina and Brachionus plicatilis)
Long term toxicity to aquatic invertebrate:
Based on the prediction done using ECOSAR version 1.1, the long term toxicity on aquatic invertebrate was predicted for test substance . On the basis of effects observed in a static freshwater system, the NOEC value for the test substance is estimated to be 20.059 mg/l for aquatic invertebrate for 21 days of exposure,The test substance is redialy biodegradable in aquatic environment it can be concluded that the test chemical can be considered as non-toxic to aquatic invertebrate at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria.
Toxicity to aquatic algae and cyanobacteria
Based on the various studies available with Klimish rating 2 for the target substance CAS NO 3088-31-1 and read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1 |
EC50 |
115.072mg/l |
growth rate |
72 hrs |
Pseudokirchnerella subcapitata |
Predicted data for target chemical |
2 |
EC50 |
100 mg/l |
Cell changes |
24 hrs |
Laminaria hyperborea |
Data from publication for CAS no 9004-82-4 |
3 |
EC50 |
117mg/l |
growth inhibition |
4 days |
Seleriastrum Capricornutum |
Data from publication for CAS no 151-21-3 |
4 |
EC50 |
1550mg/l |
growth inhibition |
6 hrs |
Seleriastrum Capricornutum |
Data from publication for CAS no 151-21-3 |
By applying weight of evidence approach to the studies summarized in the above table it can be observed that EC50 value is expected to be in range of100 to1550 mg/l in 6 hrs to 72 hrs study. Thus considering CLP Criteria for aquatic classification of the substance, it is concluded that Sodium 2-(2-dodecyloxyethoxy) ethyl sulphate does not exhibit toxicity to green algae (Pseudokirchnerella subcapitata, Laminaria hyperborea and Seleriastrum Capricornutum.)
Toxicity to microorganisms
Based on the various studies available with Klimish rating 2 for the target substance CAS NO 3088-31-1 and read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows
Sr.No |
Endpoint |
Effect values |
Basis for effects |
Duration |
Species |
Remarks |
1 |
IC50 |
5888.99 mg/l |
growth inhibition |
16 hrs |
aerobic microorganisms |
Predicted data for target chemical |
2 |
EC50
EC50 |
135 mg/l
188 mg/l |
growth inhibition |
3 hrs
0.5 hrs |
activated sludge |
Data from publication for CAS no 151-21-3 |
By applying weight of evidence approach to the studies summarized in the above table it can be observed that IC50 value is expected to be in 5888.99mg/l and EC50 value was found to be in the range of 135 to 188 mg/l in 0.5 to 16 hrs study.
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