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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

From QSAR prediction the bacterial growth inhibition test using aerobic microorganisms as the end point, the substance sodium 2-(2-dodecyloxyethoxy) ethyl sulphate was not found to inhibit growth by 50% up to the maximum tested concentration (IC50) of 5888.99 mg/l.

Key value for chemical safety assessment

EC50 for microorganisms:
5 888.99 mg/L

Additional information

Based on the various studies available with Klimish rating 2 for the target substance CAS NO 3088-31-1 and read across substances and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows




Effect values

Basis for effects






5888.99 mg/l

growth inhibition

16 hrs

aerobic microorganisms

Predicted data for target chemical






135 mg/l



188 mg/l

growth inhibition

3 hrs



0.5 hrs

activated sludge

Data from publication for CAS no 151-21-3


By applying weight of evidence approach to the studies summarized in the above table it can be observed that IC50 value is expected to be in 5888.99mg/l and EC50 value was found to be in the range of 135 to 188 mg/l in 0.5 to 16 hrs study.