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Long-term toxicity to fish

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Reference
Endpoint:
long-term toxicity to fish, other
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from ECOSAR version 1.11
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
Long term toxicity to fish was carried out according to the ECOSAR version 1.11
GLP compliance:
not specified
Specific details on test material used for the study:
sodium 2-[2-(dodecyloxy)ethoxy]ethyl sulfate / 3088-31-1 / 221-416-0
- Name of test material (as cited in study report): sodium 2-(2-dodecyloxyethoxy) ethyl sulphate
- Substance type: Organic
- Physical state: liquid
InChI: 1S/C16H34O6S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-20-13-14-21-15-16-22-23(17,18)19;/h2-16H2,1H3,(H,17,18,19);/q;+1/p-1
Smiles: C(OCCOCCCCCCCCCCCC)COS(=O)(=O)[O-].[Na+]
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
other: Fish
Test type:
static
Water media type:
freshwater
Total exposure duration:
28 d
Reference substance (positive control):
not specified
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
36.507 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: ECOSAR version 1.11
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of effects observed in a static freshwater system, the NOEC value for the substance is estimated to be 36.507 mg/l for fish for 28 days of exposure duration
Executive summary:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a static fresh water system, the NOEC value for the substance is estimated to be 36.507 mg/l for fish for 28 days of exposure duration.Since, the test substance is redialy degradable in aquatic environment, it can be concluded that the test chemical can be considered as non-toxic to fish at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria. 

Description of key information

Long term toxicity to fish:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a static fresh water system, the NOEC value for the substance is estimated to be36.507mg/l for fish for 28 days of exposure duration.Since, the test substance is redialy degradable in aquatic environment, it can be concluded that the test chemical can be considered as non-toxic to fish at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria. 

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
36 mg/L

Additional information

Long term toxicity to fish:

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a static fresh water system, the NOEC value for the substance is estimated to be36.507mg/l for fish for 28 days of exposure duration.Since, the test substance is redialy degradable in aquatic environment, it can be concluded that the test chemical can be considered as non-toxic to fish at environmentally relevant concentrations and can be considered not-classified as per the CLP classification criteria. 

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