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Environmental fate & pathways

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Based on the available data on environmental fate from the analogue substance tetramethylthiuram disulfide (CAS No. 137-26-8), conclusions related to this section could be drawn for disulfiram.

Disulfiram is considered as a not readily biodegradable and potentially adsorptive substance. However, rapid degradation in water/sediment and soil systems is expected, with half-lives below 10 days. Based on this information, disulfiram is not expected to persist in the environment. This substance is expected to be rapidly degraded in air (half-life = 19.6 minutes) and water (half-life < 10 hours) by means of photolysis. Furthermore, once released into the water, hydrolysis may play an important role in the degradation of tetraethylthiuram disulfide, especially under neutral and alkaline conditions (half-lives = 3.5 days and 6.9 hours respectively). Disulfiram is not expected to be bioaccumulative based on all available data.