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Vapour pressure

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Endpoint:
vapour pressure
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
6 September 2005- 19 October 2005
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP-Guideline study for surrogate substance
Qualifier:
according to guideline
Guideline:
other: Method A4 specified in Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC)
GLP compliance:
yes (incl. QA statement)
Remarks:
The Department of Health of the Government of The United Kingdom
Type of method:
effusion method: vapour pressure balance
Temp.:
25 °C
Vapour pressure:
0 Pa

Summary of Results

Run Log10 [Vp(25°C)]

1 -4.560

2 -5.080

3 -4.505

4 -4.322

5 -4.988

Mean -4.691

VapourPressure 2.0 x 10-5Pa

Endpoint:
vapour pressure
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from handbook or collection of data
Qualifier:
no guideline required
Temp.:
25 °C
Vapour pressure:
0.001 mm Hg
Remarks on result:
other: Estimated value

Description of key information

0.00002 Pa at 25°C

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

The vapour pressure was determined for the surrogate substance, thiram. Thiram has a lower molecular weight than disulfiram (240.4 vs. 296.5 g/mol) and is therefore more volatile than disulfiram. Adopting the measured thiram value for disulfiram is therefore inherently conservative.