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Environmental fate & pathways


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Description of key information

Tetramethylthiuram disulfide is rapidly hydrolyzed in aquatic systems (half-lives 68.5 days, 3.5 days and 6.9 hours under acidic, neutral and alkaline conditions respectively)

Key value for chemical safety assessment

Additional information

One study determining the hydrolysis of tetramethylthiuram disulfide (CAS No. 137-26-8) is available. This test was conducted according to EPA’s Pesticide Assessment Guidelines, Series 161-1, Hydrolisis Studies (1988), under GLP conditions.14C-thiram was tested at pH 5, 7 and 9, and the half-lives determined, being 68.5 days, 3.5 days and 6.9 hours respectively. Hydrolysis in alkaline and neutral conditions took place at a faster rate than under acidic conditions. The main breakdown product was CS2.


In conclusion, hydrolysis may be a relevant degradation pathway for thiram in aquatic systems.