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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: reliable, well documented GLP guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
0.12
Temp.:
20 °C
pH:
ca. 3.5 - ca. 6

Any other information on results incl. tables

The pH value of an aqeous solution is in the weak acid range, depending on concentration and the (limited) extent of hydrolysis. Because the substance has no ionizable functional groups, the partition coefficient is not dependent on the exact pH value.

The shake-flask method was not applicated, because the hazardous properties of the substance demand short handlig times.

The experimental result matches well with the results of a calculation done with the EPISUITE program (Log Pow (calc) = 1.67), which is also part of the study report.

Applicant's summary and conclusion