Registration Dossier
Registration Dossier
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EC number: 500-105-6 | CAS number: 39423-51-3 1 - 6.5 moles propoxylated
Acute Toxicity: inhalation
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Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 973
Materials and methods
- Principles of method if other than guideline:
- Six female rats exposed under static conditions to substantially saturated vapor for 8 hours and mortality recorded.
- GLP compliance:
- not specified
- Test type:
- other: no data
Test material
- Test material form:
- liquid
- Details on test material:
- Name of test material: Trimethylolpropanepoly(oxypropylene)triamine
EC no.: 500-105-6
CAS no.: 39423-51-3
Physical state: clear colourless liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: 94.2
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: no data
- Details on inhalation exposure:
- no data
- Analytical verification of test atmosphere concentrations:
- not specified
- No. of animals per sex per dose:
- 6 females
- Control animals:
- not specified
- Details on study design:
- no data
- Statistics:
- no data
Results and discussion
- Mortality:
- No animals died
- Clinical signs:
- other:
- Body weight:
- Weight at initiation was 94.2; weight at termination was 157.2
- Gross pathology:
- Nothing remarkable
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- No mortality observed
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