Registration Dossier

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973

Materials and methods

Principles of method if other than guideline:
Six female rats exposed under static conditions to substantially saturated vapor for 8 hours and mortality recorded.
GLP compliance:
not specified
Test type:
other: no data

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid
Details on test material:
Name of test material: Trimethylolpropanepoly(oxypropylene)triamine
EC no.: 500-105-6
CAS no.: 39423-51-3
Physical state: clear colourless liquid

Test animals

Species:
rat
Strain:
Wistar
Sex:
female
Details on test animals and environmental conditions:
TEST ANIMALS
- Weight at study initiation: 94.2

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
other: no data
Details on inhalation exposure:
no data
Analytical verification of test atmosphere concentrations:
not specified
No. of animals per sex per dose:
6 females
Control animals:
not specified
Details on study design:
no data
Statistics:
no data

Results and discussion

Mortality:
No animals died
Clinical signs:
other:
Body weight:
Weight at initiation was 94.2; weight at termination was 157.2
Gross pathology:
Nothing remarkable

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
No mortality observed