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EC number: 700-597-4
CAS number: 1215841-86-3
of the skin
1 2 3
E/Oe E/Oe E/Oe
formations/before dosing 0/0
of the patch
and eschar formations
The purpose of this
study was to examine trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide
for acute dermal irritation/corrosion properties in rabbits (patch
to OECD guideline 404, EC method B.4.and
OCSPP guideline 870.2500.
Under the present test conditions, none of the three male rabbits
exposed for 4 hours to 500 mg trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide/patch
(semi-occlusive conditions) showed any skin reaction. There were no
systemic intolerance reactions. Therefore, the test item was
non-irritating to skin, hence no labelling is required.
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